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870604P

Avanti

oxPAPC

Avanti Research™ - A Croda Brand 870604P, powder

Synonym(s):

oxPAPC, Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 500 μg (870604P-500ug)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870604P

lipid type

phosphoglycerides
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) is a mixture of oxidized phospholipid and a bioactive constituent of oxidized low-density lipoproteins (LDLs).

Application

Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) is suitable for use to stimulate murine alveolar macrophages in vitro. It is also suitable for use to study its effects on human aortic endothelial cell metabolic reprogramming.

Biochem/physiol Actions

Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) show barrier-protective effects on human pulmonary endothelial monolayers. This lipid induce endothelial dysfunction by stimulating both pro- and anti-inflammatory pathways. OxPAPC is highly accumulated in atherosclerotic lesions and other sites of chronic inflammation.

Packaging

5 mL Clear Glass Sealed Ampule (870604P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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