870792P

D-threo-PPMP

Avanti Research^™ - A Croda Brand 870792P, powder

• Synonym(s): 1R,2R-(+)-1-phenyl-2-palmitoylamino-3-N-morpholine-1-propanol
• Empirical Formula (Hill Notation): C₂₉H₅₀N₂O₃
• CAS Number: 139889-53-5
• Molecular Weight: 474.72
• MDL number: MFCD22495353
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 5 mg (870792P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 870792P
• lipid type: bioactive lipids; sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@H](C1=CC=CC=C1)[C@H](NC(CCCCCCCCCCCCCCC)=O)CN2CCOCC2
• InChI key: OFBANDBMHLEMFA-XRKRLSELSA-N

Description

Application

D-threo-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (D-threo-PPMP) has been used as an internal standard for the generation of standard curve in high performance liquid chromatography.

Biochem/physiol Actions

D-threo-PPMP, also known as 1R,2R-(+)-1-phenyl-2-palmitoylamino-3-N-morpholine-1-propanol, is a bioactive sphingolipid. It plays a vital role in regulation of ceramide metabolism. D-threo-PPMP influences cytokinesis failure and glycosylation by inhibiting glucosyl ceramide synthase (GCS). D-threo-PPMP also stops acylation reaction by inhibiting the activity of 1-O-acylceramide synthase (1-O-ACS).

Packaging

5 mL Amber Glass Screw Cap Vial (870792P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3