878112C

C16-18:1 PC

Avanti Research^™ - A Croda Brand 878112C

• Synonym(s): 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine
• Empirical Formula (Hill Notation): C₄₂H₈₄NO₇P
• CAS Number: 95403-34-2
• Molecular Weight: 746.09
• MDL number: MFCD11974148
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: liquid
• packaging: pkg of 1 × 1 mL (878112C-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 878112C
• concentration: 5 mg/mL (878112C-5mg)
• lipid type: phosphoglycerides; bioactive lipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COCCCCCCCCCCCCCCCC)=O
• InChI key: SIEDNCDNGMIKST-IYEJTHTFSA-N

Description

General description

C16-18:1 PC, also referred as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a platelet activating factor. It belongs to the class of bioactive lipids. HOPC is a mono-ether PC containing ester-linked 18:1 chain (oleoyl) at the sn-2 position and an ether-linked 16:0 chain (hexadecyl) at the sn-1 position.

Application

C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used: as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS), in preparation of phospholipid vesicles, as a substrate to study the substrate specificity of phospholipase B/lipase (PLB/LIP) in the presence and absence of deoxycholate (DOC).

Biochem/physiol Actions

Platelet-activating factor (PAF) acts as a lipid mediator and is involved in various inflammatory diseases.

Packaging

5 mL Clear Glass Sealed Ampule (878112C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• WGK: WGK 3