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LM1904

Avanti

17:0-20:4 PI(4,5)P2

Avanti Research™ - A Croda Brand LM1904, powder

Synonym(s):

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-4′,5′-bisphosphate) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C46H92N3O19P3
CAS Number:
1246304-70-0
Molecular Weight:
1084.15
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

manufacturer/tradename

Avanti Research™ - A Croda Brand LM1904

packaging

1 ea of 1 × (with stopper and crimp cap (LM1904-1EA))

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]

InChI

1S/C46H83O19P3.3H3N/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)62-38(36-60-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2)37-61-68(58,59)65-44-41(49)42(50)45(63-66(52,53)54)46(43(44)51)64-67(55,56)57;;;/h11,13,17,19,21,23,27,29,38,41-46

InChI key

OKMXNUJCHZSHOL-TZFFBZLFSA-N

Application

17:0-20:4 PI(4,5)P2 or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-4′,5′-bisphosphate) has been used:
  • as an internal standard in liquid chromatography tandem mass spectroscopy (LC-MS/MS) experiments
  • as a lipid standard in ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS)
  • as a standard to measure phosphatidylinositol (4,5)P2 from fibroblasts and brain samples by MS

Biochem/physiol Actions

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is critical for the phosphoinositide signaling. It acts as a primary messenger and can also as a precursor for many secondary messengers involved. PI(4,5)P2 serves as a substrate for phosphoinositide 3-kinase (PI3K) to form phosphatidylinositol 3,4,5-trisphosphate (PI3,4,5P3).

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1904-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Description
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Storage Class Code

11 - Combustible Solids

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