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404365

Sigma-Aldrich

Procion® Red MX-5B

Dye content 40 %

Synonym(s):

Reactive red 2

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150 μL
RM 2,216.00

RM 2,216.00


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150 μL
RM 2,216.00

About This Item

Empirical Formula (Hill Notation):
C19H10Cl2N6Na2O7S2
CAS Number:
Molecular Weight:
615.33
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

RM 2,216.00


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form

solid

Quality Level

composition

Dye content, 40%

mp

>300 °C (lit.)

λmax

538 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].Oc1c(\N=N\c2ccccc2)c(cc3cc(cc(Nc4nc(Cl)nc(Cl)n4)c13)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C19H12Cl2N6O7S2.2Na/c20-17-23-18(21)25-19(24-17)22-12-8-11(35(29,30)31)6-9-7-13(36(32,33)34)15(16(28)14(9)12)27-26-10-4-2-1-3-5-10;;/h1-8,28H,(H,29,30,31)(H,32,33,34)(H,22,23,24,25);;/q;2*+1/p-2/b27-26+;;

InChI key

XWZDJOJCYUSIEY-YOYNBWDYSA-L

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General description

Procion Red is a monoazo dye, that is highly soluble in water. It is used for dyeing cellulose, nylon, silk and wool.[1]

Application

Procion Red has been used in the visualization of osteocyte canalicular system.[2] It has been used as an adsorbate in the biosorption by Bacillus subtilis.[1]

Legal Information

Procion is a registered trademark of Dystar Textilfarben GmbH & Co.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hey-Kyoung Lee et al.
Cell, 112(5), 631-643 (2003-03-12)
Plasticity of the nervous system is dependent on mechanisms that regulate the strength of synaptic transmission. Excitatory synapses in the brain undergo long-term potentiation (LTP) and long-term depression (LTD), cellular models of learning and memory. Protein phosphorylation is required for
Hey-Kyoung Lee et al.
Journal of neurophysiology, 103(1), 479-489 (2009-11-13)
Activity-dependent changes in excitatory synaptic transmission in the CNS have been shown to depend on the regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs). In particular, several lines of evidence suggest that reversible phosphorylation of AMPAR subunit glutamate receptor 1 (GluR1
Hiago Murilo Melo et al.
Molecular neurobiology, 58(4), 1859-1870 (2021-01-07)
The central autonomic network, which is connected to the limbic system structures including the amygdala (AMY) and anterior hippocampus (aHIP), regulates the sympathetic and parasympathetic modulation of visceromotor, neuroendocrine, pain, and behavior manifestations during stress responses. Heart rate variability (HRV)
Xiang Cai et al.
Nature neuroscience, 16(4), 464-472 (2013-03-19)
The causes of major depression remain unknown. Antidepressants elevate concentrations of monoamines, particularly serotonin, but it remains uncertain which downstream events are critical to their therapeutic effects. We found that endogenous serotonin selectively potentiated excitatory synapses formed by the temporoammonic
Loukia Parisiadou et al.
Nature neuroscience, 17(3), 367-376 (2014-01-28)
Leucine-rich repeat kinase 2 (LRRK2) is enriched in the striatal projection neurons (SPNs). We found that LRRK2 negatively regulates protein kinase A (PKA) activity in the SPNs during synaptogenesis and in response to dopamine receptor Drd1 activation. LRRK2 interacted with

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