I1762

Isoxicam

analytical standard

• Synonym(s): 4-Hydroxy-2-methyl-N-5-methyl-3-isoxolyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
• Empirical Formula (Hill Notation): C₁₄H₁₃N₃O₅S
• CAS Number: 34552-84-6
• Molecular Weight: 335.34
• EC Number: 252-084-5
• MDL number: MFCD00079374
• UNSPSC Code: 41116107
• PubChem Substance ID: 329815356
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 200
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• SMILES string: CN1C(C(=O)Nc2cc(C)on2)=C(O)c3ccccc3S1(=O)=O
• InChI: 1S/C14H13N3O5S/c1-8-7-11(16-22-8)15-14(19)12-13(18)9-5-3-4-6-10(9)23(20,21)17(12)2/h3-7,18H,1-2H3,(H,15,16,19)
• InChI key: YYUAYBYLJSNDCX-UHFFFAOYSA-N
• Gene Information: human ... PTGS1(5742), PTGS2(5743)

Description

General description

Isoxicam is a long acting anti-inflammatory agent belonging to the oxicam group, and helps in relieving the symptoms of degenerative joint disease and rheumatoid arthritis. Its mode of action involves the ability to inhibit prostaglandin synthesis by suppressing the formation of cyclooxygenase and subsequent prostaglandin.

Application

Isoxicam may be used as an internal standard for the quantification of meloxicam in pharmaceutical preparations and as an analytical reference standard for the quantification of the analyte in biological samples using different analytical techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves