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Key Documents

SMB01354

Sigma-Aldrich

Losartan carboxylic acid

≥95% (HPLC)

Synonym(s):

EXP3174, 2-Butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid, E-3174, EXP 3174, EXP-3174

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About This Item

Empirical Formula (Hill Notation):
C22H21ClN6O2
CAS Number:
Molecular Weight:
436.89
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.21

Quality Level

Assay

≥95% (HPLC)

form

solid

shipped in

wet ice

SMILES string

Clc1nc([n](c1C(=O)O)Cc2ccc(cc2)c3c(cccc3)c4[nH]nnn4)CCCC

InChI

1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28)

InChI key

ZEUXAIYYDDCIRX-UHFFFAOYSA-N

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General description

Losartan Carboxylic Acid (E-3174) is an active carboxylic acid metabolite of Losartan. Losartan Carboxylic Acid is a potent and selective angiotensin II receptor type 1 (AT1) antagonist.

Application

Metabolomics research

Other Notes

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Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Lact. - Repr. 1B - Skin Sens. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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