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A4980

Sigma-Aldrich

Abz-FRK(Dnp)P-OH trifluoroacetate salt

≥95% (HPLC), film

Synonym(s):

o-Aminobenzoic acid-FRK(Dnp)P-OH, o-aminobenzoic acid-Phe-Arg-Lys(DNP)-Pro-OH trifluoroacetate salt, Abz-Phe-Arg-Lys(DNP)-Pro-OH

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About This Item

Empirical Formula (Hill Notation):
C39H49N11O10 · xC2HF3O2
Molecular Weight:
831.87 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

film

color

yellow

storage temp.

2-8°C

Amino Acid Sequence

Abz-Phe-Arg-Lys-DNP-Pro

Application

Abz-FRK(Dnp)P-OH trifluoroacetate (TFA) is a substrate for the Angiotensin Converting Enzyme (ACE). Abz-FRK(Dnp)P-OH TFA has been used to study both the reduction of mortality of patients with sepsis and paracetamol-induced hypothermia.

Biochem/physiol Actions

Substrate for ACE (Angiotensin Converting Enzyme). Internally quenched fluorogenic substrate for Real Time Fluorescent Assay.

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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