A6563
6-Anilinoquinoline-5,8-quinone
≥95% (TLC), solid
Synonym(s):
6-(Phenylamino)-5,8-quinolinedione, LY-83,583, LY83583
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About This Item
Empirical Formula (Hill Notation):
C15H10N2O2
CAS Number:
Molecular Weight:
250.25
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.77
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Quality Level
Assay
≥95% (TLC)
form
solid
color
violet
solubility
0.1 M HCl: 1 mg/mL
methanol: 11 mg/mL
ethanol: 8 mg/mL
storage temp.
2-8°C
SMILES string
O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13
InChI
1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H
InChI key
GXIJYWUWLNHKNW-UHFFFAOYSA-N
Application
6-Anilinoquinoline-5,8-quinone inhibits soluble guanylate cyclase and cGMP production. 6-Anilinoquinoline-5,8-quinone also blocks the release of intracellular Ca2+ and antigen-induced leukotrienes.
Biochem/physiol Actions
Blocks cGMP production; inhibits intracellular Ca2+ release; blocks the effects of nitric oxide. Inhibits antigen-induced leukotriene release.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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