D7011

Deoxyribonucleic acid sodium salt from human placenta

Type XIII

• Synonym(s): hpDNA, DNA
• CAS Number: 9007-49-2
• MDL number: MFCD00130922
• UNSPSC Code: 41106305
• NACRES: NA.51

Properties

• type: Type XIII
• form: powder
• storage temp.: 2-8°C
• InChI: 1S/C15H31N3O13P2/c16-13-1-7(20)11(28-13)5-25-32(21,22)31-9-3-15(18)29-12(9)6-26-33(23,24)30-8-2-14(17)27-10(8)4-19/h7-15,19-20H,1-6,16-18H2,(H,21,22)(H,23,24)
• InChI key: AWBASQCACWFTGD-UHFFFAOYSA-N

Description

General description

Deoxyribonucleic acid (DNA) from placenta and its methylation pattern is indicative of anomalies in the fetal growth. Tobacco smoking during pregnancy favors methylation and epigenetic modulation of placental DNA.

Application

Deoxyribonucleic acid sodium salt from human placenta has been used:

• as a standard for optimization of digestion followed by high-performance liquid chromatography (HPLC) and mass spectroscopy
• as a standard for ultra violet (UV) spectrophotometer measurements
• in polymerase chain reaction (PCR) assay and for standard curve generation for human papillomavirus type 6 quantification

Human placenta DNA (hpDNA) is a natural DNA used in studies of DNA binding anticancer agents and DNA binding agents that modulate DNA structure and function. Human placenta DNA is also used in physicochemical studies of DNA behavior in solution.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves