D8388
Dimethyl pimelimidate dihydrochloride
powder
Synonym(s):
DMP, Dimethyl pimelinediimidate dihydrochloride
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About This Item
Linear Formula:
[CH3OC(=NH)CH2CH2]2CH2 · 2HCl
CAS Number:
Molecular Weight:
259.17
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
form
powder
Quality Level
reaction suitability
reagent type: cross-linking reagent
solubility
H2O: 10 mg/mL
storage temp.
−20°C
SMILES string
Cl.Cl.COC(=N)CCCCCC(=N)OC
InChI
1S/C9H18N2O2.2ClH/c1-12-8(10)6-4-3-5-7-9(11)13-2;;/h10-11H,3-7H2,1-2H3;2*1H
InChI key
LRHXBHUTQWIZTN-UHFFFAOYSA-N
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General description
Dimethyl pimelimidate dihydrochloride is a homobifunctional cross-linking reagent used in crosslinking, protein interaction and protein modification. It typically reacts with primary amines in the pH range 7.0-10.0 to form amidine bonds.
Application
Dimethyl pimelimidate dihydrochloride has been used to develop a technique for isolating Enterocytozoon bieneusi spores directly from human stool samples with a high degree of purity, which opens up new approaches for studying this parasite.
Caution
The reagent is readily hydrolyzed at neutral pH.
Other Notes
Note that the amidine linkage preserves original primary amine positive charge. Incorporates a seven atom linker.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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