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F8509

Sigma-Aldrich

Fumaric acid

BioReagent, suitable for cell culture

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About This Item

Linear Formula:
HOOCCH=CHCOOH
CAS Number:
Molecular Weight:
116.07
Beilstein:
605763
EC Number:
MDL number:
UNSPSC Code:
12352207
eCl@ss:
39021709
PubChem Substance ID:
NACRES:
NA.71
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vapor pressure

1.7 mmHg ( 165 °C)

product line

BioReagent

Assay

≥98%

form

powder

autoignition temp.

1364 °F

expl. lim.

40 %

technique(s)

cell culture | mammalian: suitable

mp

298-300 °C (subl.) (lit.)

SMILES string

OC(=O)\C=C\C(O)=O

InChI

1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+

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1 of 4

This Item
SAB4503321C7729SAB5700197
antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

human, mouse, rat

species reactivity

human

species reactivity

human, rat

species reactivity

human, mouse, rat

Gene Information

human ... CASP8(841)

Gene Information

human ... CASP8(841)

Gene Information

human ... CASP9(842)
rat ... Casp9(58918)

Gene Information

human ... CASP8(841)

Application

A TCA (Krebs cycle) molecule used as a supplement in insect and mammalian cell culture.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

523.4 °F

Flash Point(C)

273 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ming-Zi Zhang et al.
American journal of translational research, 9(12), 5548-5557 (2018-01-10)
Apoptosis is a process of programmed cell death that occurs in multicellular organisms. The mitochondrial pathway plays a paramount role in apoptosis. In this study, the expression levels of key factors in the mitochondrial pathway and the cell proliferation factor
Augustine T Nkembo et al.
Current cancer drug targets, 19(10), 838-851 (2019-03-28)
Non-small cell lung cancers (NSCLC) harboring mutation-induced dysregulation of Ras signaling present some of the most difficult-to-manage cases, since directly targeting the constitutively active mutant Ras proteins has not resulted in clinically useful drugs. Therefore, modulating Ras activity for targeted
A A Szczepańska et al.
Prostaglandins & other lipid mediators, 143, 106336-106336 (2019-05-22)
Peroxisome proliferator-activated receptors (PPARs) are expressed in bovine uterus, and their agonists are arachidonic acid (AA) metabolites. We hypothesised that silencing of PPAR genes in bovine endometrial stromal cells (ESC) would change the intracellular signalling through PPAR and affect apoptosis
Xiao Yang Wang et al.
Clinical & experimental ophthalmology, 42(6), 529-538 (2013-11-15)
The aim of the study was to investigate, using a native mitomycin-C-resistant human Tenon's fibroblast cell line, the possibility that interferon-alpha and gamma could be used with Fas agonists as an alternative anti-fibrotic strategy to mitomycin-C in trabeculectomy. A clinically
Hanghui Wang et al.
International journal of oncology, 45(1), 157-164 (2014-04-17)
The specific and efficient delivery of small interfering RNA (siRNA) into cancer cells in vivo remains a major obstacle. In this study, we investigated whether ultrasound-targeted microbubble destruction (UTMD) combined with dual targeting of HSP72 and HSC70 in prostate cancer cell

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