G9887

γ-Globulins from sheep

≥99% (agarose gel electrophoresis)

• Synonym(s): Gamma globulin
• CAS Number: 9007-83-4
• EC Number: 232-706-1
• MDL number: MFCD01114257
• UNSPSC Code: 12352202
• NACRES: NA.61

Properties

• biological source: sheep
• Quality Level: 200
• Assay: ≥99% (agarose gel electrophoresis)
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: ≤4% NaCl
• storage temp.: −20°C

Description

General description

γ-Globulin molecules is made up of four polypeptide chains, of which two have molecular weights of about 50,000 and two of about 20,000. These chains are cross-linked by disulfide bonds.

Application

γ-Globulins from sheep were used to study the influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI. It was used in a study to test the interstitial transport of rabbit and sheep antibodies in normal and neoplastic tissues. It was also used in a study to test the enhanced progesterone and testosterone secretion, and depressed estradiol secretion in vitro from small white follicle cells of incubating turkey hens.

Preparation Note

Prepared from Cohn Fraction II, III

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves