H135
5-Hydroxydecanoic acid sodium salt
≥97% (HPLC)
Synonym(s):
5-hydroxydecanoate sodium salt
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All Photos(4)
About This Item
Empirical Formula (Hill Notation):
C10H19NaO3
CAS Number:
Molecular Weight:
210.25
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥97% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 10 mg/mL, clear
SMILES string
[Na+].CCCCCC(O)CCCC([O-])=O
InChI
1S/C10H20O3.Na/c1-2-3-4-6-9(11)7-5-8-10(12)13;/h9,11H,2-8H2,1H3,(H,12,13);/q;+1/p-1
InChI key
YNAGNECWEKMWRM-UHFFFAOYSA-M
Biochem/physiol Actions
Blocks post-ischemic actions of the K+ channel activator cromakalim.
Features and Benefits
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Caution
Hygroscopic
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Asger Andersen et al.
Cardiology, 123(3), 177-180 (2012-11-07)
We investigated whether ischemic preconditioning (IPC) protects the right ventricular (RV) myocardium against ischemic injury in hearts treated with the specific mitochondrial ATP-sensitive potassium (K(ATP)) channel blocker 5-hydroxydecanoate (5-HD). Hearts from male Wistar rats (300 g, n = 39) were
Ischemic preconditioning of the right ventricle: a new application for an old concept?.
Tuvia Ben Gal et al.
Cardiology, 123(3), 175-176 (2012-11-07)
Sze Man Wong et al.
Chinese medicine, 6(1), 7-7 (2011-02-16)
Danshen-Gegen decoction (DG), a Chinese herbal formula, has been demonstrated to be effective for the treatment of coronary heart disease such as myocardial infarction. In the present study, we investigated the effect of DG post-conditioning on isoproterenol (ISO)-induced myocardial injury
Garrett J Gross et al.
Pharmacology, 90(1-2), 110-116 (2012-07-21)
Eribis peptide 94 (EP 94) is a new enkephalin derivative which potently binds to the µ- and δ-opioid receptor. In this study, we determined the effects of EP 94 and potential mechanism(s) involved in cardioprotection of the rat heart. An
Ischemia reperfusion injury, KATP channels, and exercise-induced cardioprotection against apoptosis.
John C Quindry et al.
Journal of applied physiology (Bethesda, Md. : 1985), 113(3), 498-506 (2012-06-02)
Exercise is a potent stimulus against cardiac ischemia reperfusion (IR) injury, although the protective mechanisms are not completely understood. The study purpose was to examine whether the mitochondrial or sarcolemmal ATP-sensitive potassium channel (mito K(ATP) or sarc K(ATP), respectively) mediates
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