H5257

Hispidin

solid, ≥98% (HPLC)

• Synonym(s): 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone
• Empirical Formula (Hill Notation): C₁₃H₁₀O₅
• CAS Number: 555-55-5
• Molecular Weight: 246.22
• MDL number: MFCD01866972
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278468
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• storage condition: protect from light
• color: yellow to brown
• mp: 237.5-238.5 °C
• solubility: DMSO: >10 mg/mL
• storage temp.: −20°C
• SMILES string: OC1=CC(/C=C/C(O2)=CC(O)=CC2=O)=CC=C1O
• InChI: 1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+
• InChI key: SGJNQVTUYXCBKH-HNQUOIGGSA-N
• Gene Information: human ... PRKACB(5567), PRKAR2B(5577), PRKCB(5579)

Description

General description

Hispidin is a phenolic compound, that is obtained from a medicinal mushroom, Phellinus linteus.

Biochem/physiol Actions

Hispidin exhibits robust antioxidant, anticancer and antidiabetic properties. It has the ability to guard against peroxynitrite-mediated cytotoxicity, DNA damage and the development of hydroxyl radicals.

Potent inhibitor of protein kinase C_β, cytotoxic for cancer cells.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): No data available
• Flash Point(C): No data available
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves