I1142

Monoclonal Anti-Interferon-γ antibody produced in rat

clone 37895, purified immunoglobulin, lyophilized powder

• Synonym(s): Anti-IFN-γ
• MDL number: MFCD00165744
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rat
• Quality Level: 200
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 37895, monoclonal
• form: lyophilized powder
• species reactivity: mouse
• technique(s): flow cytometry: suitable; neutralization: suitable; western blot: suitable
• isotype: IgG2a
• UniProt accession no.: P01580
• storage temp.: −20°C
• Gene Information: mouse ... Ifng(15978)

Description

General description

Interferon-γ (IFN-γ) belongs to Type II class of interferons and is produced by T helper cells (specifically, Th1 cells), natural killer (NK) and natural killer T (NKT) cells and cytotoxic T cells (TC cells) . It has various biological functions including antiviral activity like inhibition of cell or tumor growth, act as a potent modulator of immune responses and modifies cellular processes as well as stimulates the differentiation of B cells into immunoglobulin-producing cells. Monoclonal Anti-Interferon-γ antibody can be used in immunoblotting. Rat anti-Interferon-γ antibody has shown no cross-reactivity for recombinant human IFN-γ or recombinant rat IFN-γ.

Specificity

The antibody does not cross-react with recombinat human IFN-γ or recombinant rat IFN-γ.

Immunogen

recombinant mouse IFN-γ.

Application

Monoclonal Anti-Interferon-γ antibody can be used in neutralization and indirect ELISA.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline and 5% trehalose.

Preparation Note

Purified from cell culture supernatant using protein G.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves