I2760

(−)-Isoproterenol (+)-bitartrate salt

powder

• Synonym(s): (−)-Isoprenaline (+)-bitartrate salt
• Empirical Formula (Hill Notation): C₁₁H₁₇NO₃ · C₄H₆O₆
• CAS Number: 54750-10-6
• Molecular Weight: 361.34
• MDL number: MFCD00069361
• UNSPSC Code: 51111800
• PubChem Substance ID: 24277773
• NACRES: NA.77

Properties

• form: powder
• Quality Level: 200
• color: white to off-white
• solubility: H₂O: ≥50 mg/mL, clear, colorless to faintly yellow
• originator: Sanofi Aventis
• SMILES string: O[C@@H]([C@H](O)C(O)=O)C(O)=O.CC(C)NC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C11H17NO3.C4H6O6/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;5-1(3(7)8)2(6)4(9)10/h3-5,7,11-15H,6H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m00/s1
• InChI key: LBOPECYONBDFEM-RWALOXMOSA-N
• Gene Information: human ... ADRB1(153), ADRB2(154), ADRB3(155)

Description

Application

(−)-Isoproterenol (+)-bitartrate salt has been used:

• as a component in KRH medium for cyclic adenosine monophosphate (cAMP) assay
• to stimulate preadipocytes to study its concentration responsive curve
• to intraperitoneally administer to mice to evaluate whether the multi-dry-electrode plate (MDEP)-sensor system can assess drug responses

Biochem/physiol Actions

β-Adrenoceptor agonist; increases cytosolic cAMP.

Isoproterenol functions as an ovine pulmonary vein dilator.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3