I8000

2-Iodosobenzoic acid

≥98% (TLC)

• Synonym(s): IBA
• Linear Formula: OIC₆H₄CO₂H
• CAS Number: 304-91-6
• Molecular Weight: 264.02
• Beilstein: 1939973
• EC Number: 206-159-4
• MDL number: MFCD00002401
• UNSPSC Code: 12352209
• PubChem Substance ID: 24896131
• NACRES: NA.26

Properties

• Product Name: 2-Iodosobenzoic acid,
• Assay: ≥98% (TLC)
• Quality Level: 200
• form: powder
• color: white to off-white
• mp: 230 °C (dec.) (lit.)
• storage temp.: −20°C
• SMILES string: OC(=O)c1ccccc1[I]=O
• InChI: 1S/C7H5IO3/c9-7(10)5-3-1-2-4-6(5)8-11/h1-4H,(H,9,10)
• InChI key: IFPHDUVGLXEIOQ-UHFFFAOYSA-N

Description

Application

For cleavage of tryptophanyl peptide bonds.

Biochem/physiol Actions

2-Iodosobenzoic acid (IBA) may be used to study enzyme structure and activity. IBA is used as an oxidant which oxidizes vicinal sulfhydryls to disulfides (cysteine residues) within enzymes leading to their inactivation or conformational changes. IBA is also used to cleave tryptophanyl peptide bonds.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves