K3750
L-Kynurenine sulfate salt
≥98% (HPLC), suitable for ligand binding assays
Synonym(s):
β-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
C10H12N2O3 · H2SO4
CAS Number:
Molecular Weight:
306.29
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Recommended Products
Product Name
L-Kynurenine sulfate salt, crystalline
Assay
≥98% (HPLC)
Quality Level
form
crystalline
technique(s)
ligand binding assay: suitable
color
light yellow
storage temp.
−20°C
SMILES string
OS(O)(=O)=O.N[C@@H](CC(=O)c1ccccc1N)C(O)=O
InChI
1S/C10H12N2O3.H2O4S/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15;1-5(2,3)4/h1-4,8H,5,11-12H2,(H,14,15);(H2,1,2,3,4)/t8-;/m0./s1
InChI key
KAXRWMOLNJZCEW-QRPNPIFTSA-N
Related Categories
Application
L-Kynurenine sulfate salt has been used as a substrate to study the enzyme activity of kynurenine aminotransferase. It has also been used in the synthesis of Kyn adducts of certain amino acids .
Biochem/physiol Actions
Key intermediate in the breakdown pathway of tryptophan.
L-Kynurenine (L-Kyn) is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mammals, it modulates the transmission of glutamate neurotransmitter. It is also considered to be a sex-attracting pheromone in vertebrates.
L-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. L-kynurenine is involved in a variety of neurological processes and diseases. L-kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service