M0627

7-Methylguanosine

≥90%

• Empirical Formula (Hill Notation): C₁₁H₁₅N₅O₅
• CAS Number: 20244-86-4
• Molecular Weight: 297.27
• Beilstein: 3713683
• MDL number: MFCD16661197
• UNSPSC Code: 41106305
• PubChem Substance ID: 24896562
• NACRES: NA.51

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥90%
• form: powder
• solubility: water: 50 mg/mL, clear to hazy, colorless to faintly yellow
• storage temp.: 2-8°C
• SMILES string: C[n+]1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13
• InChI: 1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/t4-,6-,7-,10-/m1/s1
• InChI key: OGHAROSJZRTIOK-KQYNXXCUSA-N

Description

General description

7-Methylguanosine structure is also referred to as a cap. It is located on the 5′ end of the cytoplasmic mRNA.

Application

7-Methylguanosine has been used in the removal of residual phosphates from pre rigor solution, phosphate mop system and phosphorous standard solution.

Biochem/physiol Actions

7-Methylguanosine is involved in the processing of a cap-dependent translational process of mRNA. It is also involved in protecting the mRNA from degradation due to ribonucleases and mediate nuclear export. 7-Methylguanosine also permits the recruitment of ribosome.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves