M7920

Minoxidil Sulfate

• Synonym(s): U-58838
• Empirical Formula (Hill Notation): C₉H₁₅N₅O₄S
• CAS Number: 83701-22-8
• Molecular Weight: 289.31
• MDL number: MFCD06248907
• UNSPSC Code: 12352107
• PubChem Substance ID: 24897202
• NACRES: NA.77

Properties

• form: powder
• Quality Level: 200
• originator: Johnson & Johnson
• storage temp.: −20°C
• SMILES string: Nc1cc(nc(N)[n+]1OS([O-])(=O)=O)N2CCCCC2
• InChI: 1S/C9H15N5O4S/c10-7-6-8(13-4-2-1-3-5-13)12-9(11)14(7)18-19(15,16)17/h6H,1-5H2,(H4,10,11,12,15,16,17)
• InChI key: OEOLOEUAGSPDLT-UHFFFAOYSA-N

Description

Application

Minoxidil sulfate (MXS) has been used as a drug agent to study its effects on alopecia in corticotropin-releasing factor over-expressing (CRF-OE) mice. It has also been used as a positive control in an assay for the culturing of rat vibrissa follicles.

Biochem/physiol Actions

Minoxidil sulfate (MXS) is an endogenous derivative of minoxidil. It possesses greater aqueous solubility and is a potent vasodilator. MXS has the potential to treat androgenic alopecia or male baldness.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Active metabolite of minoxidil.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves