N115

Naltrindole hydrochloride

≥97.5% (HPLC), solid, δ-opioid receptor antagonist

• Synonym(s): NTI hydrochloride
• Empirical Formula (Hill Notation): C₂₆H₂₆N₂O₃ · HCl
• CAS Number: 111469-81-9
• Molecular Weight: 450.96
• MDL number: MFCD00069313
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278062
• NACRES: NA.77

Properties

• Product Name: Naltrindole hydrochloride, solid
• form: solid
• Quality Level: 100
• storage condition: desiccated
• color: off-white
• solubility: methanol: 4.5 mg/mL; H₂O: 8 mg/mL
• storage temp.: −20°C
• SMILES string: Cl[H].Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)c6[nH]c7ccccc7c6C[C@@]35O)CC8CC8
• InChI: 1S/C26H26N2O3.ClH/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14;/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2;1H/t20-,24+,25+,26-;/m1./s1
• InChI key: KNJKRQXCFJCQHC-IDRHMUJXSA-N
• Gene Information: human ... OPRD1(4985)

Description

Biochem/physiol Actions

Highly selective, non-peptide δ-opioid receptor antagonist that crosses the blood-brain barrier.

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves