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Product Name
Protamine sulfate salt from herring, Grade III, histone, free(Millon test)
biological source
fish (herring)
Quality Level
type
Grade III
form
powder
impurities
histone, free (Millon test)
solubility
6 M HCl: 25 mg/mL, clear, colorless to very faintly yellow
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Application
May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer.
Biochem/physiol Actions
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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