PRS2221

Anti-BAFF antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-BLyS, Anti-Tall, Anti-Thank, Anti-Tumor necrosis factor (ligand) superfamily, member 13b
• MDL number: MFCD02265860
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: predicted mol wt 31 kDa
• species reactivity: human, rat, mouse
• technique(s): immunocytochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: Q9Y275
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... TNFSF13B(10673)

Description

General description

B-lymphocyte activating factor (BAFF/TNFSF13B) is a cytokine that belongs to the TNF (tumor necrosis factor) superfamily. BAFF is located on human chromosome 13q33.

Immunogen

a peptide corresponding to amino acids near the carboxy-terminus of human BAFF.

Biochem/physiol Actions

B cell activating factor (BAFF) participates in B cell and T cell mediated immunity. It plays a key role in the survival and differentiation of B cells. Mutations in BAFF regulates the levels of antibody. BAFF also participates in enhancing the responses of IL-6 (interlukin-6) and TNF-α (tumor necrosis factor alpha), that helps hepatocytes in the production of acute-phase protein.

Linkage

The action of this antibody can be blocked using blocking peptide SBP2221.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable