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SAB1402660

Sigma-Aldrich

Monoclonal Anti-ACVR1C antibody produced in mouse

clone 2E3, purified immunoglobulin, buffered aqueous solution

Synonym(s):

ACVRLK7, ALK7

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1 EA
CA$89.60

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CA$89.60


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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2E3, monoclonal

form

buffered aqueous solution

mol wt

antigen ~35.9 kDa

species reactivity

human

technique(s)

indirect ELISA: suitable
proximity ligation assay: suitable

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This Item
SAB2100044SAB1403523WH0000091M9
Gene Information

human ... ACVR1C(130399)

Gene Information

human ... ACVR1C(130399)

Gene Information

human ... ACVR1B(91)

Gene Information

human ... ACVR1B(91)

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

species reactivity

human

species reactivity

horse, human, rabbit, bovine

species reactivity

human

species reactivity

human

clone

2E3, monoclonal

clone

polyclonal

clone

6D3, monoclonal

clone

1C1, monoclonal

biological source

mouse

biological source

rabbit

biological source

mouse

biological source

mouse

General description

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM

Immunogen

ACVR1C (AAH22530.1, 23 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPM

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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