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Key Documents

SCP0181

Sigma-Aldrich

[D-Lys6]-LH-RH Free Acid

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About This Item

Empirical Formula (Hill Notation):
C59H83N17O14
Molecular Weight:
1254.40
UNSPSC Code:
12352209
NACRES:
NA.32

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥72%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Lys-Leu-Arg-Pro-Gly

Application

Luteinizing-hormone-releasing hormone (LHRH) (GnRH) is a decapeptide (pyroQHWSYKLRPG-NH2) trophic hormone that regulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. Various analogues have been developed using D-amino acids to increase resistance to degradation. These analogues are used as potential targeting agents in the development of chemotherapies and as possible agonists and antagonist of the LHRH receptor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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