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Key Documents

SML0087

Sigma-Aldrich

MEGX

≥95% (HPLC)

Synonym(s):

MGEX, Monoethylglycinexylidide, N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide, Norlidocaine

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About This Item

Empirical Formula (Hill Notation):
C12H18N2O
CAS Number:
Molecular Weight:
206.28
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=C(NC(CNCC)=O)C(C)=CC=C1

InChI

1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15)

InChI key

WRMRXPASUROZGT-UHFFFAOYSA-N

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Application

MEGX has been used in an approach to improve the yield of N-dealkylated lidocaine.

Biochem/physiol Actions

Lidocaine metabolite
MEGX is generated by hepatic cytochrome P-450 system upon oxidative de-ethylation. Measurement of MEGX by immunoassay contributes to liver function test. MEGX possesses antiarrhythmic action and therefore extends lidocaine effect.
Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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