SML0679

Danshensu sodium salt

≥98% (HPLC)

• Synonym(s): (R)-α,3,4-Trihydroxy-benzenepropanoic acid sodium salt, (R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid, 3-(3′,4′-Dihydroxyphenyl)-(2R)-lactic acid sodium salt, DS 182, Dan Shen Su, Dan shen suan A, Salianic acid A, Salvianic acid A
• Empirical Formula (Hill Notation): C₉H₉O₅ · Na
• CAS Number: 81075-52-7
• Molecular Weight: 220.15
• MDL number: MFCD07781415
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825582
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +30 to +40°, c = 1 in H₂O
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC1=C(O)C=CC(C[C@@H](O)C([O-])=O)=C1.[Na+]
• InChI: 1S/C9H10O5.Na/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14;/h1-3,8,10-12H,4H2,(H,13,14);/q;+1/p-1/t8-;/m1./s1
• InChI key: ZMMKVDBZTXUHFO-DDWIOCJRSA-M

Description

Biochem/physiol Actions

Danshensu is an active component of Salvia miltiorrhiza (Danshen) that suppresses the formation of reactive oxygen species, inhibits platelet adhesion and aggregation, and protects myocardium against ischemia. Danshensu is cardioprotective, which protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation.

Danshensu is cardioprotective, which protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable