SML1886
VPC-13566
≥98% (HPLC)
Synonym(s):
2-(7-Methyl-1H-indol-3-yl)quinoline
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About This Item
Empirical Formula (Hill Notation):
C18H14N2
CAS Number:
Molecular Weight:
258.32
UNSPSC Code:
51111800
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
CC1=CC=CC2=C1NC=C2C3=NC4=CC=CC=C4C=C3
InChI key
FPKBNOVQNMJTEJ-UHFFFAOYSA-N
Biochem/physiol Actions
VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor.
VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor. VPC-13566 potently inhibits AR transcriptional activity by displacement of the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines including an enzalutamide-resistant cell line and inhibits the growth of AR-dependent prostate cancer xenograft in mice.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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