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Key Documents

SML1994

Sigma-Aldrich

BOP

>97% (HPLC)

Synonym(s):

N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt

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About This Item

Empirical Formula (Hill Notation):
C25H28N3NaO7S
CAS Number:
Molecular Weight:
537.56
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

>97% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

Biochem/physiol Actions

BOP (N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt) is a potent and selective dual inhibitor of integrins alpha-4 beta-1 (α4β1) and alpha-9 beta-1 (α9β1) with Kd values in the picomolar range. BOP has been shown to preferentially mobilize hematopoietic stem cells (HSCs) and progenitors and to act synergistically with AMD3100.
Dual α9β1/α4β1 integrin inhibitor

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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