SML3258

3-Methyl-5-(2,2,3-trimethyl-3-cyclopentenyl)pentan-2-ol

≥90% (GC)

• Synonym(s): 3-Methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pentan-2-ol
• Empirical Formula (Hill Notation): C₁₄H₂₆O
• CAS Number: 65113-99-7
• Molecular Weight: 210.36
• MDL number: MFCD00672185
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥90% (GC)
• form: oil
• color: white to beige
• storage temp.: −20°C
• SMILES string: CC1=CCC(CCC(C)C(C)O)C1(C)C
• InChI: 1S/C14H26O/c1-10(12(3)15)6-8-13-9-7-11(2)14(13,4)5/h7,10,12-13,15H,6,8-9H2,1-5H3
• InChI key: NGYMOTOXXHCHOC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Agonist of olfactory receptor OR2AT4

Sandalore is an agonist of olfactory receptor OR2AT4, a G-protein-coupled receptor (GPCR) also expressed in human primary keratinocytes. Sandalore was shown to enhance hair growth in human scalp hair follicles by stimulating OR2AT4, resulting in decreased apoptosis and increased production of the anagen-prolonging growth factor IGF-1. Sandalore had previously been shown to increase wound healing. Sandalore was also recently used to study OR2AT4 found in the human chronic myelogenous leukemia (CML) cell line K562 and in white blood cells of clinically diagnosed acute myeloid leukemia (AML) patients.

Safety Information

• Pictograms: GHS09
• Hazard Statements: H411
• Precautionary Statements: P273 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2