SRP4038

Fgf-2 from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

• Synonym(s): FGF-b, Fibroblast Growth Factor-basic, HBGF-2 Prostatropin
• MDL number: MFCD00081382
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: mouse
• recombinant: expressed in E. coli
• Assay: ≥95% (HPLC); ≥95% (SDS-PAGE)
• form: lyophilized
• mol wt: ~16.3 kDa
• packaging: pkg of 50 μg
• storage condition: avoid repeated freeze/thaw cycles
• impurities: endotoxin, tested
• NCBI accession no.: P15655
• UniProt accession no.: P15655
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... Fgf2(14173)

Description

General description

FGF-2 (fibroblast growth factor 2) is a basic heparin binding growth factor. It is ubiquitously expressed and belongs to the FGF family. It is also referred to as BFGF (basic fibroblast growth factor). The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.

Biochem/physiol Actions

FGF-2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. It is present in the preimplantation embryos and is important for proper development. It is also responsible for angiogenesis. FGF-2 plays a crucial role in adipogenesis and development of adipose tissues. It is associated with tumor growth and metastasis.

Physical form

Sterile filtered and Lyophilized without additives.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in sterile water to 100 μg/mL.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable