T0178

apo-Transferrin bovine

≥98%

• CAS Number: 11096-37-0
• EC Number: 234-318-8
• MDL number: MFCD00130536
• UNSPSC Code: 12352202
• NACRES: NA.61

Properties

• biological source: bovine
• Assay: ≥98%
• form: powder
• technique(s): cell culture | mammalian: suitable
• solubility: H₂O: 20 mg/mL
• UniProt accession no.: Q29443
• storage temp.: 2-8°C
• Gene Information: bovine ... TF(280705)

Description

Application

All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves