T3068
Thrombin generation chromogenic substrate
≥90% (HPLC), solid
Synonym(s):
β-Ala-Gly-Arg-p-nitroanilide diacetate
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About This Item
Empirical Formula (Hill Notation):
C21H34N8O9
Molecular Weight:
542.54
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.32
Recommended Products
biological source
synthetic (organic)
Quality Level
Assay
≥90% (HPLC)
form
solid
technique(s)
activity assay: suitable
storage temp.
2-8°C
SMILES string
[N+](=O)([O-])c1ccc(cc1)NC(=O)[C@@H](NC(=O)CNC(=O)CCN)CCCNC(=N)N.OC(=O)C.OC(=O)C
InChI key
PBMJNSQKWBTVOL-GXKRWWSZSA-N
Amino Acid Sequence
Ala-Gly-Arg-pNA
Application
Thrombin generation chromogenic substrate can be used for chromogenic assay developed through aptamer affinity capture and a subsequent enzyme reaction for detecting the thrombin in dilute human serum.
Biochem/physiol Actions
Thrombin generation chromogenic substrate also known as beta-Ala-Gly-Arg para-nitroanilide, is proteolytically cleaved by human thrombin and produces beta-Ala-Gly-Arg and p-nitroanilide. The release of p-nitroanilide is quatified for assesing the anti-thrombin activity.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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