V0377
[Arg8]-Vasopressin solution
Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl
Synonym(s):
β-Hypophamine, AVP, Antidiuretic hormone, Arginine vasopressin
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50 I.U.
₩190,719
100 I.U.
₩340,025
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50 I.U.
₩190,719
100 I.U.
₩340,025
About This Item
Empirical Formula (Hill Notation):
C46H65N15O12S2
CAS Number:
Molecular Weight:
1084.23
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.32
Biological source:
synthetic (organic)
Form:
liquid
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This Item | V6879 | AB1565 | SAB1301597 |
|---|---|---|---|
| biological source synthetic (organic) | biological source synthetic (organic) | biological source rabbit | biological source rabbit |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| concentration ~100 IU/mL in 0.9% NaCl | concentration - | concentration - | concentration - |
| form liquid | form powder | form - | form buffered aqueous solution |
| Gene Information human ... AVP(551) | Gene Information human ... AVP(551) | Gene Information human ... AVP(551) | Gene Information human ... AVP(551) |
| pH ~3.5 | pH - | pH - | pH - |
![[Arg8]-Vasopressin solution Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl](/deepweb/assets/sigmaaldrich/product/structures/326/242/dede8c26-cf73-4a28-a5d9-1d57c673cf0e/640/dede8c26-cf73-4a28-a5d9-1d57c673cf0e.png)
Amino Acid Sequence
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]
Application
Biochem/physiol Actions
Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg8-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).
Endogenous antidiuretic hormone in most mammalian species; neurotransmitter in the central nervous system implicated in a variety of physiological processes including diuresis, vasoregulation, and memory.
[Arg8]-Vasopressin solution also known as Antidiuretic hormone, Arginine vasopressin or beta-Hypophamine is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock.[3] It stimulates three acid-base transporters and hence increases the capability of the cell to regulate pH.[4]
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
235.4 °F - closed cup
Flash Point(C)
113 °C - closed cup
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J J McDonnell et al.
The Anatomical record, 240(4), 528-536 (1994-12-01)
Beta-endorphin and oxytocin immunocytochemical localization were examined in the neurointermediate lobe (lobus nervosus and pars intermedia) of the bovine hypophysis in order to describe the anatomical distribution of these two neurointermediate lobe hormones. Twenty-seven bovine hypophyses were collected from slaughterhouse
Vasopressin antagonists for patients with acute heart failure: interpreting new clinical and translational data.
A M Feldman et al.
Clinical pharmacology and therapeutics, 95(4), 373-375 (2013-12-19)
Natalie Yuen et al.
American journal of physiology. Cell physiology, 306(10), C931-C942 (2014-03-22)
Brain edema forms rapidly in the early hours of ischemic stroke by increased secretion of Na, Cl, and water into the brain across an intact blood-brain barrier (BBB), together with swelling of astrocytes as they take up the ions and
Vanessa Vezzi et al.
Scientific reports, 10(1), 9111-9111 (2020-06-06)
Vasopressin receptor 2 (V2R) mutations causing the nephrogenic syndrome of inappropriate antidiuresis (NSIAD) can generate two constitutively active receptor phenotypes. One type results from residue substitutions in several V2R domains and is sensitive to vaptan inverse agonists. The other is
Daniel J van Wamelen et al.
Sleep, 36(1), 117-125 (2013-01-05)
To study whether sleep and circadian rhythm disturbances in patients with Huntington's disease (HD) arise from dysfunction of the body's master clock, the hypothalamic suprachiasmatic nucleus. Postmortem cohort study. Eight patients with HD and eight control subjects matched for sex
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