V6879

[Lys⁸]-Vasopressin

≥98% (HPLC)

• Synonyme(s) : Lysine vasopressin, Lyspressin
• Formule empirique (notation de Hill) : C₄₆H₆₅N₁₃O₁₂S₂
• CAS Number: 50-57-7
• Poids moléculaire : 1056.22
• Numéro CE : 200-050-5
• Numéro MDL: MFCD00133970
• Code UNSPSC : 51111800
• ID de substance PubChem : 24900764
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Stérilité: non-sterile
• Essai: ≥98% (HPLC)
• Forme: powder
• Solubilité: 0.1 M acetic acid: 20 mg/mL, clear, colorless
• Numéro d'accès UniProt: P01185
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: CC(O)=O.NCCCCC(NC(=O)C1CCCN1C(=O)C2CSSCC(N)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(Cc4ccccc4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O
• InChI: 1S/C46H65N13O12S2.C2H4O2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34;1-2(3)4/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69);1H3,(H,3,4)
• Clé InChI: NKWAIKZITYLOMT-UHFFFAOYSA-N
• Informations sur le gène: human ... AVP(551)

Description

Amino Acid Sequence

Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 [Disulfide Bridge: 1-6]

Application

[Lys⁸]-Vasopressin was used as a test compound in quantitative analysis of peptides and proteins by using on-line capillary isoelectric focusing-mass spectrometry.The product was used for studying the coupling of a polymer-based microchip electrophoresis to MALDI-TOF MS by using rotating ball interface.

Actions biochimiques/physiologiques

Predominant form of vasopressin present in pigs and marsupials. It has lower vasopressor and antidiuretic activity than Arg⁸-vasopressin.

[Lys⁸]-Vasopressin also refers as Lysine vasopressin or Lyspressin is the predominant form of vasopressin present in pigs and marsupials. It antagonizes the amnesia in rats. Lyspressin can also induce resistance to extinction of active avoidance behaviour.

Notes préparatoires

2 mg of [Lys8]-Vasopressin dissolves in 0.1 mL, 0.1M HOAc to yield a clear, colorless solution.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves