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569250-U

Supelco

Discovery® HS C18 (3 µm) HPLC Columns

L × I.D. 5 cm × 4.6 mm, HPLC Column

Synonym(s):

Discovery RP18 HPLC Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Pricing and availability is not currently available.
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Product Name

Discovery® HS C18 HPLC Column, 3 μm particle size, L × I.D. 5 cm × 4.6 mm

material

stainless steel column

Quality Level

100

Agency

suitable for USP L1

product line

Discovery®

feature

endcapped

manufacturer/tradename

Discovery®

packaging

1 ea of

extent of labeling

20% Carbon loading

parameter

≤70 °C temp. range
400 bar pressure (5801 psi)

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1 of 4

This Item
568513-U568500-U568501-U
Discovery® HS C18 HPLC Column 3 μm particle size, L × I.D. 5 cm × 4.6 mm

569250-U

Discovery® HS C18 HPLC Column

Discovery® HS C18 HPLC Column 5 μm particle size, L × I.D. 25 cm × 4 mm

568513-U

Discovery® HS C18 HPLC Column

Discovery® HS C18 HPLC Column 5 μm particle size, L × I.D. 5 cm × 2.1 mm

568500-U

Discovery® HS C18 HPLC Column

Discovery® HS C18 HPLC Column 5 μm particle size, L × I.D. 10 cm × 2.1 mm

568501-U

Discovery® HS C18 HPLC Column

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

L × I.D.

5 cm × 4.6 mm

L × I.D.

25 cm × 4 mm

L × I.D.

5 cm × 2.1 mm

L × I.D.

10 cm × 2.1 mm

matrix active group

C18 (octadecyl) phase

matrix active group

C18 (octadecyl) phase

matrix active group

C18 (octadecyl) phase

matrix active group

C18 (octadecyl) phase

particle size

3 μm

particle size

5 μm

particle size

5 μm

particle size

5 μm

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

matrix

silica gel, high purity, spherical particle platform, fully porous particle

pore size

120 Å

pore size

120 Å

pore size

120 Å

pore size

120 Å

Application


  • A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies.: This study developed a robust RP-HPLC method to determine molnupiravir in various nanoformulations, showcasing its potential application in permeability studies and ensuring drug stability (Reçber et al., 2022) (Reçber et al., 2022).

  • Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.: This research presented an HPLC-UV method for analyzing terizidone in plasma, facilitating its use in pharmacokinetic studies of patients with drug-resistant tuberculosis (Mulubwa and Mugabo, 2018) (Mulubwa and Mugabo, 2018).

  • Optimization of LC method for the quantification of doxorubicin in plasma and urine samples in view of pharmacokinetic, biomedical and drug monitoring therapy studies.: The study optimized an LC method for quantifying doxorubicin in plasma and urine, crucial for pharmacokinetic, biomedical, and drug monitoring therapy applications (Maliszewska et al., 2018) (Maliszewska et al., 2018).

Features and Benefits

  • Stable, low bleed for LC-MS applications
  • Scalable from analytical to preparatory
  • Highly stable to ensure excellent run-to-run and lot-to-lot reproducibility
  • Higher hydrophobicity for better resolution of difficult analytes
   

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Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Description
Pricing

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    Certificates of Analysis (COA)

    Lot/Batch Number
    280848-06
    280848-05
    280848-04
    280848-03
    280848-02

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    T S Anirudhan et al.
    Journal of environmental radioactivity, 116, 141-147 (2012-11-17)
    The use of a carboxylate-functionalized graft copolymer (PGTDC-COOH) based on titanium dioxide-densified cellulose (TDC) for the removal and recovery of thorium(IV) [Th(IV)] from industrial wastewater is reported in this paper. Infrared spectroscopy and X-ray diffractometer were used to characterize the
    Pengcheng Du et al.
    Colloids and surfaces. B, Biointerfaces, 102, 1-8 (2012-09-22)
    The magnetic-targeting stimuli-responsive hollow polymeric microspheres show unique performance as the intelligent carriers for the site specific controlled delivery of drugs or genes. In the work, the well-defied dual-responsive double-walled hollow microspheres with movable magnetic cores were prepared from the
    Alireza Shalviri et al.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(3), 587-597 (2012-09-22)
    This work investigated the capability of a new nanoparticulate system, based on terpolymer of starch, polymethacrylic acid and polysorbate 80, to load and release doxorubicin (Dox) as a function of pH and to evaluate the anticancer activity of Dox-loaded nanoparticles
    Qiangying Yi et al.
    Langmuir : the ACS journal of surfaces and colloids, 28(29), 10822-10829 (2012-06-27)
    Microcapsules composed of weak polyelectrolytes modified with UV-responsive benzophenone (BP) groups were fabricated by the layer-by-layer (LbL) technique. Being exposed to UV lights, capsules shrunk in the time course of minutes at irradiation intensity of 5 mW/cm(2). The shrinkage adjusted
    Svetlana V Pavlukhina et al.
    ACS applied materials & interfaces, 4(9), 4708-4716 (2012-08-23)
    We developed a highly efficient, biocompatible surface coating that disperses bacterial biofilms through enzymatic cleavage of the extracellular biofilm matrix. The coating was fabricated by binding the naturally existing enzyme dispersin B (DspB) to surface-attached polymer matrices constructed via a
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