C1605

Z-Val-Asp(O-Me)-Val-Ala-Asp(O-Me) fluoromethyl ketone

powder, ≥95%

• Synonym(s): Z-VDVAD-FMK
• Linear Formula: C₃₂H₄₆N₅O₁₁F
• CAS Number: 210344-92-6
• Molecular Weight: 695.73
• MDL number: MFCD03452881
• UNSPSC Code: 12352209
• PubChem Substance ID: 329774898
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• Assay: ≥95%
• form: powder
• color: white
• solubility: DMSO: soluble
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)OC)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(=O)CF
• InChI: 1S/C32H46FN5O11/c1-17(2)26(30(44)34-19(5)28(42)35-21(23(39)15-33)13-24(40)47-6)37-29(43)22(14-25(41)48-7)36-31(45)27(18(3)4)38-32(46)49-16-20-11-9-8-10-12-20/h8-12,17-19,21-22,26-27H,13-16H2,1-7H3,(H,34,44)(H,35,42)(H,36,45)(H,37,43)(H,38,46)/t19-,21-,22-,26-,27-/m0/s1
• InChI key: ANTIWMNLIROOQF-IREHUOSBSA-N
• Gene Information: human ... CASP2(835) ; mouse ... CASP2(12366) ; rat ... CASP2(64314)

Description

Amino Acid Sequence

Z-Val-Asp-OMe-Val-Ala-Asp-OMe-FMK

Biochem/physiol Actions

A cell-permeable inhibitor of caspase-2, which exhibits competitive and irreversible inhibition.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves