N6784

Noggin/Fc Chimera from mouse

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

• MDL number: MFCD03457756
• UNSPSC Code: 51111800
• NACRES: NA.32

Properties

• biological source: mouse
• Quality Level: 100
• recombinant: expressed in NSO cells
• Assay: >95% (SDS-PAGE)
• form: lyophilized powder
• mol wt: 55-60 kDa by SDS-PAGE (reducing); calculated mol wt 50 kDa
• packaging: pkg of 50 μg
• impurities: endotoxin, tested
• UniProt accession no.: P97466
• storage temp.: −20°C
• Gene Information: mouse ... Nog(18121)

Description

Biochem/physiol Actions

Binds and blocks the acitivity of bone morphogenetic proteins (BMPs).

Binds and blocks the acitivity of bone morphogenetic proteins (BMPs). Mature mouse noggin shares 99% and 83% sequence identity with human and Xenopus noggin, respectively.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by its ability to inhibit recombinant human BMP-4 induced alkaline phosphatase activity in ATDC5 cells.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves