116238

5,7-Dimethoxycoumarin

98%

• Synonym(s): Citropten, Limettin
• Empirical Formula (Hill Notation): C₁₁H₁₀O₄
• CAS Number: 487-06-9
• Molecular Weight: 206.19
• EC Number: 207-646-4
• MDL number: MFCD00006870
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847274
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• form: solid
• mp: 146-149 °C (lit.)
• functional group: ester
• SMILES string: COc1cc(OC)c2C=CC(=O)Oc2c1
• InChI: 1S/C11H10O4/c1-13-7-5-9(14-2)8-3-4-11(12)15-10(8)6-7/h3-6H,1-2H3
• InChI key: NXJCRELRQHZBQA-UHFFFAOYSA-N

Description

General description

5,7-dimethoxycoumarin is isolated and identified from leaves and fruits of Pelea anisata H. Mann, a plant whose fruit are used in the construction of mohikana leis. It induces frameshift mutagenesis in bacteria. It also causes lethal photosensitization and the formation of sister chromatid exchanges in Chinese hamster cells.

Biochem/physiol Actions

5,7-Dimethoxycoumarin induces the processes of differentiation and melanogenesis in murine (B16) and human (A375).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)