130036

N-Methyl-4-piperidone

97%

• Synonym(s): 1-Methyl-4-piperidinone
• Empirical Formula (Hill Notation): C₆H₁₁NO
• CAS Number: 1445-73-4
• Molecular Weight: 113.16
• Beilstein/REAXYS Number: 106924
• EC Number: 215-895-5
• MDL number: MFCD00006191
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847937
• NACRES: NA.22

Properties

• reg. compliance: suitable for FDA C-010.02
• Quality Level: 100
• assay: 97%
• form: liquid
• density: 0.92 g/mL at 25 °C (lit.)
• application(s): PFAS testing
• functional group: ketone
• storage temp.: 2-8°C
• SMILES string: CN1CCC(=O)CC1
• InChI: 1S/C6H11NO/c1-7-4-2-6(8)3-5-7/h2-5H2,1H3
• InChI key: HUUPVABNAQUEJW-UHFFFAOYSA-N

Description

Application

N-Methyl-4-piperidone can be used as a reactant to prepare:

• Spiropiperidine rings by reacting with malononitrile and electrophiles or Michael acceptors.
• (3E,5E)-1-Methyl-3,5-bis(phenylmethylene)-4-piperidinone by reacting with benzaldehyde via Michael addition, followed by intramolecular O-cyclization/elimination sequential reactions.
• N,N′-Dimethylbispidinone by utilizing a double Mannich condensation method.

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 136.4 °F - closed cup
• flash_point_c: 58 °C - closed cup
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)