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131474

Sigma-Aldrich

1-Phenylpyrrole

99%

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About This Item

Empirical Formula (Hill Notation):
C10H9N
CAS Number:
635-90-5
Molecular Weight:
143.19
EC Number:
211-242-3
MDL number:
MFCD00005343
UNSPSC Code:
12352100
PubChem Substance ID:
24848017
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

100

assay

99%

form

solid

bp

234 °C (lit.)

mp

58-60 °C (lit.)

SMILES string

c1ccc(cc1)-n2cccc2

InChI

1S/C10H9N/c1-2-6-10(7-3-1)11-8-4-5-9-11/h1-9H

InChI key

GEZGAZKEOUKLBR-UHFFFAOYSA-N

Related Categories

General description

1-Phenylpyrrole inhibited cytochrome P-450 dependant monooxygenase activity in microsomes from rat liver[1].

Application

1-Phenylpyrrole was used to study the half-wave potentials of the aqueous redox couples and the oxidation potentials of the monomers in 1,2-dichloroethane[2].

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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    STBK1762
    STBJ8769
    STBJ2956
    STBH8129
    STBH1545

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    Yuan Xiao Zhu et al.
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    Georg Petzold et al.
    Nature, 532(7597), 127-130 (2016-02-26)
    Thalidomide and its derivatives, lenalidomide and pomalidomide, are immune modulatory drugs (IMiDs) used in the treatment of haematologic malignancies. IMiDs bind CRBN, the substrate receptor of the CUL4-RBX1-DDB1-CRBN (also known as CRL4(CRBN)) E3 ubiquitin ligase, and inhibit ubiquitination of endogenous
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    Donovan KA, et al.
    eLife, 7, e38430-e38430 (2018)
    Antoine Domenger et al.
    Frontiers in oncology, 13, 1110916-1110916 (2023-02-14)
    Multiple Myeloma (MM) is an incurable neoplasm of mature B cells and the second most prevalent hematological malignancy worldwide. While combinations of proteasome inhibitors like bortezomib (Bz) and immunomodulators (IMiDs) like lenalinomide (Len) are generally effective in newly diagnosed patients
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