132527

(S)-(+)-2-Amino-1-butanol

≥98%

• Linear Formula: C₂H₅CH(NH₂)CH₂OH
• CAS Number: 5856-62-2
• Molecular Weight: 89.14
• Beilstein/REAXYS Number: 1718930
• EC Number: 227-475-9
• MDL number: MFCD00064418
• UNSPSC Code: 12352116
• PubChem Substance ID: 24848057
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: ≥98%
• form: liquid
• optical activity: [α]20/D +10°, neat
• optical purity: ee: 96% (GLC)
• refractive index: n20/D 1.4521 (lit.)
• bp: 172-174 °C (lit.)
• density: 0.944 g/mL at 25 °C (lit.)
• functional group: amine; hydroxyl
• SMILES string: CC[C@H](N)CO
• InChI: 1S/C4H11NO/c1-2-4(5)3-6/h4,6H,2-3,5H2,1H3/t4-/m0/s1
• InChI key: JCBPETKZIGVZRE-BYPYZUCNSA-N

Description

Application

(S)-(+)-2-Amino-1-butanol is a chiral amino alcohol that may be used in the synthesis of (S)-2-(6-benzylamino-9-isopropyl-9H-purin-2-ylamino) butan-1-ol, an (S)-enantiomer of roscovitine. It can also be used to synthesize homochiral 2-methylpyrroles. (S)-(+)-2-Amino-1-butanol is an intermediate for the synthesis of (S,S)-ethambutol, an antibacterial agent for treating tuberculosis.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 203.0 °F - closed cup
• flash_point_c: 95 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter