135828

Benzamide

99%

• Synonym(s): Benzoic acid amide
• Linear Formula: C₆H₅CONH₂
• CAS Number: 55-21-0
• Molecular Weight: 121.14
• Beilstein/REAXYS Number: 385876
• EC Number: 200-227-7
• MDL number: MFCD00007968
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848219
• NACRES: NA.22

Properties

• assay: 99%
• mp: 125-128 °C (lit.)
• solubility: ethanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to light yellow
• functional group: amide; phenyl
• SMILES string: NC(=O)c1ccccc1
• InChI: 1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
• InChI key: KXDAEFPNCMNJSK-UHFFFAOYSA-N
• Gene Information: human ... PARP1(142)

Description

General description

Benzamide on radioiodination by different labeling procedures results in large-scale production of radioiodinated benzamides having potential therapeutic application for patients with metastatic malignant melanoma.

Benzamide is used as a building block in organic synthesis for the preparation of various biologically active compounds.

Application

Benzamide was used to study the mechanism of photocatalytic decomposition of aqueous solution of acetic acid, acetamide and acetonitrile in the presence of semiconductors. It was used to develop a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Biochem/physiol Actions

Inhibits poly(ADP-ribose) polymerase (PARP).

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H341
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Muta. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 356.0 °F - closed cup
• flash_point_c: 180 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves