144525

2,3-Dichloroquinoxaline

96%

• Empirical Formula (Hill Notation): C₈H₄Cl₂N₂
• CAS Number: 2213-63-0
• Molecular Weight: 199.04
• Beilstein/REAXYS Number: 126076
• EC Number: 218-667-3
• MDL number: MFCD00006720
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848664
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 96%
• form: solid
• mp: 152-154 °C (lit.)
• functional group: chloro
• SMILES string: Clc1nc2ccccc2nc1Cl
• InChI: 1S/C8H4Cl2N2/c9-7-8(10)12-6-4-2-1-3-5(6)11-7/h1-4H
• InChI key: SPSSDDOTEZKOOV-UHFFFAOYSA-N

Description

General description

2,3-Dichloroquinoxaline reacts with 6-aminothiouracil in ethanol/TEA to form 6-amino-2-(3-chloroquinoxalin-2-ylthio)pyrimidin-4(3H)-one. It reacts with cholest-5-en-3-one semicarbazone/thiosemicarbazone to form steriodal cholest-5-en-3-oxazolo and thiazoloquinoxaline.

Application

2,3-Dichloroquinoxaline was used in the synthesis of mono and 2,3-disubstituted quinoxalines. It was used in solid phase synthesis of HPLC chiral stationary phase containing the N,N′-dialkyl-2,3-diaminoquinoxaline group as a linking structure.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H319,H335
• pcodes: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges