144894

4-Amino-3-methylphenol

97%

• Synonym(s): 2-Amino-5-hydroxytoluene, 4-Amino-m-cresol, 4-Hydroxy-2-methylaniline
• Linear Formula: H₂NC₆H₃(CH₃)OH
• CAS Number: 2835-99-6
• Molecular Weight: 123.15
• Beilstein/REAXYS Number: 2078803
• EC Number: 220-621-2
• MDL number: MFCD00007871
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848689
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 97%
• form: solid
• mp: 176-179 °C (lit.)
• SMILES string: Cc1cc(O)ccc1N
• InChI: 1S/C7H9NO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,8H2,1H3
• InChI key: QGNGOGOOPUYKMC-UHFFFAOYSA-N

Description

General description

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

Application

4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding.

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H317,H410
• pcodes: P261 - P264 - P273 - P280 - P301 + P312 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1A
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves