157910

Methyl bromoacetate

97%

• Synonym(s): 2-Bromoacetic acid methyl ester, Bromoacetic acid methyl ester, Carbomethoxymethyl bromide, Methyl α-bromoacetate, Methyl 2-bromoacetate, Methyl 2-bromoethanoate
• Linear Formula: BrCH₂COOCH₃
• CAS Number: 96-32-2
• Molecular Weight: 152.97
• Beilstein/REAXYS Number: 506256
• EC Number: 202-499-2
• MDL number: MFCD00000189
• UNSPSC Code: 12352100
• PubChem Substance ID: 24849708
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 97%
• form: liquid
• refractive index: n20/D 1.458 (lit.)
• bp: 51-52 °C/15 mmHg (lit.)
• density: 1.616 g/mL at 25 °C (lit.)
• functional group: bromo; ester
• SMILES string: COC(=O)CBr
• InChI: 1S/C3H5BrO2/c1-6-3(5)2-4/h2H2,1H3
• InChI key: YDCHPLOFQATIDS-UHFFFAOYSA-N

Description

General description

Methyl bromoacetate is an α-bromo ester. Reactions of the methyl bromoacetate with conjugate base of (methylmethoxycarbene)pentacarbonylchromium(0) yields alkylated carbene complexes.

Application

Methyl bromoacetate was used in the synthesis of novel coumarins. It was also employed in the synthesis of cis-cyclopropanes.

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H301,H314,H317
• pcodes: P261 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1C - Skin Sens. 1
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 147.2 °F - closed cup
• flash_point_c: 64 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter