158623

Phenoxyacetyl chloride

98%

• Linear Formula: C₆H₅OCH₂COCl
• CAS Number: 701-99-5
• Molecular Weight: 170.59
• Beilstein/REAXYS Number: 607585
• EC Number: 211-862-4
• MDL number: MFCD00000726
• UNSPSC Code: 12352100
• PubChem Substance ID: 24849768
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• refractive index: n20/D 1.534 (lit.)
• bp: 225-226 °C (lit.)
• density: 1.235 g/mL at 25 °C (lit.)
• functional group: acyl chloride; phenoxy
• SMILES string: ClC(=O)COc1ccccc1
• InChI: 1S/C8H7ClO2/c9-8(10)6-11-7-4-2-1-3-5-7/h1-5H,6H2
• InChI key: PKUPAJQAJXVUEK-UHFFFAOYSA-N

Description

Application

Phenoxyacetyl chloride was used in the synthesis of:

• series of macrocyclic bis-β-lactams
• 5-phenyl-6-epiphenoxymethylpenicillin benzyl ester
• N-protected guanosine derivatives, useful in RNA synthesis
• phenyloxyketene, for cycloaddition to imines leading to β-lactams

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H314,H335
• pcodes: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH014
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter