171824

DL-Proline

99%, for peptide synthesis, ReagentPlus^®

• Synonym(s): (±)-Pyrrolidine-2-carboxylic acid
• Empirical Formula (Hill Notation): C₅H₉NO₂
• CAS Number: 609-36-9
• Molecular Weight: 115.13
• Beilstein/REAXYS Number: 80812
• EC Number: 210-189-3
• MDL number: MFCD00005250
• UNSPSC Code: 12352209
• PubChem Substance ID: 24850387
• NACRES: NA.22

Properties

• Product Name: DL-Proline, ReagentPlus^®, 99%
• Quality Level: 100
• product line: ReagentPlus^®
• assay: 99%
• form: powder
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 208 °C (dec.) (lit.)
• application(s): peptide synthesis
• SMILES string: OC(=O)C1CCCN1
• InChI: 1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
• InChI key: ONIBWKKTOPOVIA-UHFFFAOYSA-N

Description

General description

DL-Proline, also known as 2-pyrrolidinylcarboxylic acid, is an amino acid commonly used in solution-phase peptide synthesis due to its ability to act as a turn inducer resulting from its restricted phi( ϕ) angle.

Application

DL-Proline can be is used in the preparation of cis-aminoproline-alkene (cis-Apa)linker, which is further used as an intermediate compound for the synthesis of cyclic pseudopeptides via solution phase peptide synthesis.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)