183938

2,3,5,6-Tetramethylpyrazine

98%

• Synonym(s): 2,3,5,6-Tetramethylpyrazine, Ligustrazin, Ligustrazine, Tetrapyrazine
• Empirical Formula (Hill Notation): C₈H₁₂N₂
• CAS Number: 1124-11-4
• Molecular Weight: 136.19
• Beilstein/REAXYS Number: 113100
• EC Number: 214-391-2
• MDL number: MFCD00006146
• UNSPSC Code: 12352100
• eCl@ss: 39161809
• PubChem Substance ID: 24851081
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• form: solid
• bp: 190 °C (lit.)
• mp: 77-80 °C (lit.)
• SMILES string: Cc1nc(C)c(C)nc1C
• InChI: 1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
• InChI key: FINHMKGKINIASC-UHFFFAOYSA-N

Description

General description

2,3,5,6-Tetramethylpyrazine has been isolated from Ephedra sinica. It is useful in the treatment of several disorders such as asthma, heart failure, rhinitis and urinary incontinence. It is a flavor ingredient of tobacco. It forms cocrystal with 4-hydroxybenzoic acid which exhibits supramolecular synthon polymorphism.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves